Every night, the Tropicana cabaret offers its performance "Viaje al Caribe" (a Journey to the Caribbean), which narrates the history of the people of Santiago, the most Caribbean city in Cuba, where one can feel the influence of Haiti and its voodoo religion and French customs, Dominican Republic and its merengue, Jamaica and its reggae and Puerto Rico among others. Dinner and show in the same style as the famous Tropicana Cabaret from Havana. This modern facility has been elegantly decorated with traditional elements that blend-in with the lush natural vegetation surrounding the area

This Spanish-colonial mansion was the birthplace of poet José María Heredia, who, because of his pro-independence writings, is considered Cuba's first national poet. Heredia died in 1839 at age 36 while exiled in Mexico. The house, now just a fraction of its original size, displays period furniture and some of the poet's works and belongings. The home's traditional interior patio is planted with trees and plants—including orange, myrtle, palm, and jasmine—associated with Heredia's verse. A marble plaque on the house's Calle Heredia facade excerpts one of the poet's most famous works, "Niágara".

This venue is one of the symbols of Santiago de Cuba, where traditional rhythms such as the trova, bolero and son were born. Situated very close to the Parque Céspedes, it is the meeting place for 'trovadores', both old and new. Considered one of the most important cultural institutions in Cuba, it preserves a musical movement that is deeply-rooted in the traditions of Santiago and forms an integral part of the city's life.

The museum of the Clandestine Struggle is located Padre Pico steps up. This excellent museum, in one of the city’s finest colonial houses, focuses on the activities of the resistance movement under local martyr Frank País. Residents of Santiago were instrumental in supporting the Revolution, as were peasants in the Sierra Maestra. From the museum’s balcony, there are tremendous views of Santiago and the bay.