The most atmospheric part of the city is Old Santiago. Céspedes Park constitutes the political, religious, administrative and social center more important of the city. The attractive square is a genteel place with tall trees, gas lanterns and iron benches. In their perimeter were located by disposition of the Laws of Indias, the representative buildings of the power: Town Hall, Cathedral, the house of the governors and the mansions of the main families of the village. Parque Céspedes is dominated by its twin-towered cathedral. A basilica was built on this spot in 1528, but what you see was rebuilt in the early 19th century after a series of earthquakes and fires.

The museum of the Clandestine Struggle is located Padre Pico steps up. This excellent museum, in one of the city’s finest colonial houses, focuses on the activities of the resistance movement under local martyr Frank País. Residents of Santiago were instrumental in supporting the Revolution, as were peasants in the Sierra Maestra. From the museum’s balcony, there are tremendous views of Santiago and the bay.

Cuba's oldest museum was founded in 1899 by Emilio Bacardí Moreau, the former Santiago mayor whose rum-making family fled to Puerto Rico after the Revolution. It is just a few metres from the Parque Céspedes, in the heart of the city. The museum has an excellent collection of Cuban art, as well as some European works, some items from the wars of independence and an archaeological hall that features a 3,000-year-old Egyptian mummy, two Peruvian skeletons and a shrunken head. It houses the most important painting gallery in Cuba, displaying an enviable collection of colonial painting dating back two centuries.

The Basilica of Our Lady of Charity of El Cobre, the Patron Saint of Cuba, can be found 27 km from the city centre, in a mining town founded in 1830. The Basilica stands on a gentle hill and contains display cases with items such as the medal received by the writer Ernest Hemingway on being awarded the Nobel Prize for Literature in 1954. The story of the Virgin dates from the early 1600s, when three men in a boat first saw her floating on water during a storm; tradition holds that the Virgin saved the men from certain drowning. Records show that the statue was most likely brought from Spain on order of the then-governor of Cuba, but don't play iconoclast with the millions of faithful who take seriously the Virgin's reputed miraculous powers. Our Lady of Charity of El Cobre was crowned by Pope John Paul II in 1998, during his visit to Cuba. Every 8th of September, her feast day, thousands of pilgrims come here to give thanks and beg favours of the blessed virgin.