Situated in the former Presidential Palace (1920-1960), the Museum of the Revolution is a colorful building of a large dome and a mixture of styles. A detailed panorama of the struggle undertaken by the Cuban people in order to obtain its freedom is available in its 38 rooms. Its outdoor areas feature the Granma Memorial, where visitors can see, protected by an enormous glass case, the boat on which Fidel Castro and more than eighty combatants returned to Cuba from exile in Mexico to recommence the fight for the country's independence.

The Santo Ángel Custodio Church was built in 1695, but wasn’t considered a church until 1788. It lies on one of the few and modest hills of the city, called Loma del Ángel. The original church was severely affected by the 1846 hurricane, its tower and the whole of the front and back of the nave were destroyed, so it was completely refurbished in the peculiar gothic style that can be seen today. Currently, the temple has two towers and an atrium where the church’s cemetery was formerly located. The entry doors are in the shape of pointed arches, and in its interior has three naves covered by barrel vault, as well as an ambulatory, the only church in Cuba to contain this feature. Félix Varela and José Martí were baptised in this church. It is also interesting to know that this temple is mentioned in Cecilia Valdés, a great 19th century Cuban novel by Cirilo Villaverde.

Plaza de Armas surrounds a statue of the patriot Céspedes and is ringed by shaded marble benches and second-hand bookstalls. This square, founding in 1519, was the city's first open space, around which the most important political, military, religious and civil institutions were located. The palaces that surrounded it during the 18th century are worthy exponents of Cuban Baroque architecture. On the square’s eastern side a small neoclassical temple, El Templete, marks the spot where the first Catholic mass was celebrated in 1519. Next door is one of the city’s most luxurious hotels, Hotel Santa Isabel. To the north, the squat but angular and moated Castillo de la Real Fuerza (Fort of the Royal Forces) is one of the oldest forts in the Americas.  

The neighbors of the town insisted to the town council on the need to create a new public square for their amusement. In 1587, the town council decided to use as a public square the area behind the Convento de San Francisco, which was being built at the time. During the latter decades of the 16th century, this square was called the Plaza Nueva (new square), but from the 18th century onwards, once the Plaza del Cristo had been built, it began to become known as the Plaza Vieja (old square). The most remarkable feature of this square are the buildings around it, with their unquestionable historical and artistic importance of having been the blueprint for a style of architecture which, along with certain developments, subsequently spread throughout the city and characterised the Cuban architecture of the 18th century.